Acute fipronil intoxication in Squirrel Monkey (Saimiri sciureus)

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dc.contributor.authorDemir, Onur
dc.contributor.authorÖzdemir, Özgen
dc.contributor.authorKoçak, Asiye
dc.contributor.authorArslan, Zeynel
dc.contributor.authorSevin, Sedat
dc.contributor.departmentVeteriner Fakültesitr_TR
dc.date.accessioned2021-10-11T14:20:15Z
dc.date.available2021-10-11T14:20:15Z
dc.date.issued2021-03-31
dc.description.abstractA biocidal product in gel form containing 0.05% fipronil active substance was used for pest control in the habitat of thirteen Squirrel Monkey (Saimiri sciureus) in a zoo. Following the application, sudden death was observed in three primates. Routine bacteriological, histopathological and toxicological analyses on one cadaver and tissue samples from the cadaver did not produce any pathogenic agent, pesticide and any pathognomonic findings. In an attempt to investigate the presence of known fipronil intoxication biomarkers, fipronil and fipronil sulfone, we applied modified QuEChERS extraction processes on tissue samples and determined the fipronil and fipronil sulfone levels as 27.1-3.5 μg/kg in cutaneous tissue and 13.8-47.2 μg/kg in brain tissue, respectively, by using UHPLC Q-Orbitrap Mass Spectrometer. In the light of the anamnesis, necropsy, microbiology and histopathology results, and after evaluating the presence of fipronil-fipronil sulfone in tissues, we considered that the deaths could have resulted from acute fipronil toxicity due to species-specific active substance susceptibility.tr_TR
dc.identifier.endpage184tr_TR
dc.identifier.issn/e-issn1308-2817
dc.identifier.issue2tr_TR
dc.identifier.startpage181tr_TR
dc.identifier.urihttps://doi.org/10.33988/auvfd.739352tr_TR
dc.identifier.urihttp://hdl.handle.net/20.500.12575/75389
dc.identifier.volume68tr_TR
dc.language.isoentr_TR
dc.publisherAnkara Üniversitesitr_TR
dc.relation.isversionof10.33988/auvfd.739352tr_TR
dc.relation.journalAnkara Üniversitesi Veteriner Fakültesi Dergisitr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıtr_TR
dc.subjectBiocidaltr_TR
dc.subjectFiproniltr_TR
dc.subjectFipronil sulfonetr_TR
dc.titleAcute fipronil intoxication in Squirrel Monkey (Saimiri sciureus)tr_TR
dc.typeArticletr_TR

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Cilt:68 Sayı:02 (2021)