Histological study of a corrective influence of a compound potassium 2-((4-amino-5-(morpholinomethyl)- 4h-1,2,4-triazol-3-yl)thio)acetate (pkr-173) on the state of chicken's liver under infection by pseudomonas aeruginosa
No Thumbnail Available
Date
2020
Journal Title
Journal ISSN
Volume Title
Publisher
Ankara Üniversitesi
Abstract
otassium 2((4-amino-5-(morpholinomethyl)-4H-1,2,4-triazol-3yl)thio)acetate (PKR-173) with different
antibiotics on the state of chicken's liver under infection by Pseudomonas aeruginosa.
Material and Method: The histological study was carried out on the levers of intact chickens (intact
control); chickens that were infected by the strain of Pseudomonas aeruginosa (controlled pathology); chickens
that had (before being infected by Pseudomonas aeruginosa) preventive input of the compound PKR-173 with the classic antibiotic Enrofloxacin or with Saroflox (undergoing research); or were input Thiotriazolin with the
classic antibiotic Enrofloxacin.
Result and Discussion: As a result, it is stated, that preventive input of the compound PKR-173 with
reseachable antibiotic Saroflox, as well as with classic antibiotic Enrofloxacin and Thiotriazolin with antibiotic
Enrofloxacin, to chickens infected with pseudomonas aeruginosa, prevents from chickens' livers developing
stereotypical morphological changes characteristic of nonspecific reactive hepatitis. Analysis of quantitative
characteristics of pathological process that developed in chicken's liver infected with pseudomonas aeruginosa,
and the corrective influence of researched methods showed that the compound PKR-173 with antibiotic Saroflox
believably lowers displays of all signs of pathology compared to the controlled pathology
Description
Keywords
Hepatitis, Hepatoprotective effect, Infection of pseudomonas, Saroflox