Determination of the levels of serum oxidative indicator, cytokine and some biochemical parameters in horses naturally infected with Theileria equi

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dc.contributor.authorÖzdek, Uğur
dc.contributor.authorOğuz, Bekir
dc.contributor.authorKömüroğlu, Ahmet Ufuk
dc.contributor.authorDeğer, Yeter
dc.contributor.departmentVeteriner Fakültesitr_TR
dc.date.accessioned2021-10-08T08:14:27Z
dc.date.available2021-10-08T08:14:27Z
dc.date.issued2020-06-03
dc.description.abstractEquine theileriosis is considered as a serious problem because of harmful effects on the health and performance of equids. Despite the importance of this disease, there are few studies in related to clinical pathologic changes in equine theileriosis especially in horses. In this study, the oxidative stress biomarkers, cytokines, enzymes, lipid profile, electrolytes, minerals and some metabolites were evaluated in horses naturally infected with Theileria equi (n=22) and healthy (n=7). In infected horses, the serum concentrations of MDA, IFN-γ, total protein, globulin, bilirubin (total, direct, indirect), triglyceride, glucose, iron, chloride, sodium and copper with enzyme activities of ALP, AST and GGT were found significantly higher, however concentrations of GSH, albumin, total cholesterol, HDL, TIBC, calcium, phosphorus, magnesium, potassium, zinc and manganese with enzyme activity of CAT were found lower when compared to the healthy horses (P<0.05). The changes in TNF-α, creatinine, urea and LDL concentrations were not statistically significant (P>0.05).The results indicate that there are significant changes in the oxidative indicator, cytokine, and biochemical parameters of horses in T. equi infection and that these changes may be useful in the evaluation of the diagnosis, prognosis and treatment of theileriosis. In addition, comprehensive studies are needed to better understand the role of cytokines in the pathogenesis of theileriosis.tr_TR
dc.identifier.endpage263tr_TR
dc.identifier.issn/e-issn1308-2817
dc.identifier.issue3tr_TR
dc.identifier.startpage257tr_TR
dc.identifier.urihttps://doi.org/10.33988/auvfd.603305tr_TR
dc.identifier.urihttp://hdl.handle.net/20.500.12575/75336
dc.identifier.volume67tr_TR
dc.language.isoentr_TR
dc.publisherAnkara Üniversitesitr_TR
dc.relation.isversionof10.33988/auvfd.603305tr_TR
dc.relation.journalAnkara Üniversitesi Veteriner Fakültesi Dergisitr_TR
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıtr_TR
dc.subjectBiochemical parametertr_TR
dc.subjectTheileria equitr_TR
dc.subjectCytokinetr_TR
dc.titleDetermination of the levels of serum oxidative indicator, cytokine and some biochemical parameters in horses naturally infected with Theileria equitr_TR
dc.typeArticletr_TR

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Cilt:67 Sayı:03 (2020)